Search Results - aleksandra+sikora

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Background of Invention Each year witnesses roughly 78 million new gonorrhea infections [etiologic agent Neisseria gonorrhoeae (Ng)] worldwide. While often asymptomatic (particularly in females), untreated infection can lead to pelvic inflammatory disease, ectopic pregnancy, infertility, and increased transmission/acquisition of HIV. Although antimicrobials...

Published: 4/6/2022 | Inventor(s): Aleksandra Sikora, Ryszard Zielke, Ann Jerse

Keywords(s): Gonorrhea, vaccine

Category(s): Vaccines

Peptide Inhibitors of Gonorrhoeae

Technology Description Antigonococcal peptide inhibitors of Neisseria gonorrhoeae that act against a non-conventional new target, nitrite reductase AniA, that is necessary for N. gonorrhoeae anaerobic respiration and biofilm formation. The anaerobic life style is an important state during disease and favored in biofilms, which form in cervical gonococcal...

Published: 12/23/2021 | Inventor(s): Aleksandra Sikora, Konstantin Korotkov

Keywords(s): Antibiotics, Antimicrobial, Drug, Drug Development, Gonorrhea, Inhibitor, Microbiology, Peptide, Therapeutic

Category(s): Therapeutics, Vaccines