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The use of PD-1, LAG-3 and TIGIT as biomarkers of HIV persistence during antiretroviral therapy
Value Proposition: Antiretroviral therapy (ART) reduces HIV replication but does not cure HIV. The persistence of HIV in a small pool of long-lived latently infected resting CD4 T cells is a major barrier to viral eradication. Identification of cellular markers that are preferentially expressed at the surface of latently infected cells paves the way...
Published: 1/15/2016   |   Inventor(s): Remi Fromentin, Nicolas Chomont, Rafick Sekaly
Keywords(s): Diagnostics, Diagnostics - Infectious Disease, Therapeutics, Therapeutics - Infectious Diseases
Category(s): Therapeutics, Vaccines, Diagnostics
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