Search Results - marcelo rubinstein

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Transgenic mice expressing a red fluorescent protein in proopiomelanocortin neurons, granule cell neurons of the hippocampal dentate gyrus, pituitary corticotrophs, and pituitary melanotrophs
This technology is a transgenic mouse strain expressing a red fluorescent protein in proopiomelanocortin (POMC) neurons, granule cell neurons of the hippocampal dentate gyrus, pituitary corticotrophs, and pituitary melanotrophs. Jackson Lab Stock #009593.
Published: 12/21/2016   |   Inventor(s): Malcolm Low, Veronica Otero-Corchon, Marcelo Rubinstein
Keywords(s): Biological Materials, Biological Materials - Mice
Category(s): Biological Materials, Research Tools
POMC transgenic mice and neuron-specific promoter
Technology OverviewPOMC neurons of the hypothalamus are critical components of the neural circuitry controlling appetite, feeding, and metabolism. In addition they modulate the activity of other hypothalamic neurons which control reproduction, thyroid hormone levels, growth hormone secretion and neuroendocrine stress responses. Genetic evidence in ...
Published: 4/28/2010   |   Inventor(s): Malcolm Low, Marcelo Rubinstein, Flavio Silva De Souza
Keywords(s): Biological Materials, Biological Materials - Mice, Therapeutics, Therapeutics - Neurology
Category(s): Research Tools
D2 Dopamine Receptor Knock-Out Mice
Technology OverviewD2R is the gene for the D2 dopamine receptor and encodes a member of the D2-like class of dopamine receptors. It is one of the most abundant dopaminergic receptors expressed in the brain. This strain could be used to screen and assess agonist and antagonist drugs specific to the D2 receptor. These mutant mice, technology #...
Published: 4/28/2010   |   Inventor(s): Malcolm Low, David Grandy, Marcelo Rubinstein, Michele Kelly
Keywords(s): Biological Materials, Biological Materials - Mice, Research Tools, Research Tools - Screening
Category(s): Biological Materials
D4 Dopamine Receptor Knock-Out Mice
Technology OverviewResearchers at OHSU have developed technology # 0379, a strain of mice that are genetically deficient in the D4 dopamine receptor. These mice provide a new animal model for the study of the function of the D4 receptor. Homozygous mice may exhibit locomotor supersensitivity to ethanol, cocaine, and methamphetamine, as well...
Published: 4/28/2010   |   Inventor(s): Malcolm Low, David Grandy, Marcelo Rubinstein
Keywords(s): Biological Materials, Biological Materials - Mice, Research Tools, Research Tools - Screening
Category(s): Biological Materials
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