Search Results - biological materials - receptors/targets

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D2 Dopamine Receptor and Genes and Associated International Patents
 
Published: 1/29/2015   |   Inventor(s): Olivier Civelli, James Bunzow, David Grandy, Curtis Machida
Keywords(s): Biological Materials, Biological Materials - Receptors/Targets, Research Tools, Research Tools - Screening
Category(s): Biological Materials, Research Tools
Yeast strain expressing human VDAC2
Technology OverviewThe voltage dependent anion channel (VDAC) proteins are the major pathways for metabolite flux through the outer membrane. These mitochondrial membrane proteins control the flux of anions through voltage gated mechanisms. VDACs have been shown to be important in apoptotic responses and linked to certain neurodegenerative disease...
Published: 5/31/2011   |   Inventor(s): Michael Forte, Elizabeth Blachly-Dyson
Keywords(s): Biological Materials, Biological Materials - Other, Biological Materials - Receptors/Targets, Research Tools, Research Tools - Screening
Category(s): Biological Materials
Yeast strain expressing human VDAC1
Technology OverviewThe voltage dependent anion channel (VDAC) proteins are the major pathways for metabolite flux through the outer membrane. These mitochondrial membrane proteins control the flux of anions through voltage gated mechanisms. VDACs have been shown to be important in apoptotic responses and linked to certain neurodegenerative disease...
Published: 5/31/2011   |   Inventor(s): Michael Forte, Elizabeth Blachly-Dyson
Keywords(s): Biological Materials, Biological Materials - Other, Biological Materials - Receptors/Targets, Research Tools, Research Tools - Screening
Category(s): Biological Materials
cDNA Clone Encoding the RGK5 (Kv1.3) Voltage-Gated Potassium Channel
Technology # 0382 OverviewLow stringency hybridization screening of a rat genomic DNA library with a previously described cDNA clone encoding a rat voltage-gated potassium channel has resulted in the characterization of a member of the potassium channel family, RGK5. An uninterrupted nucleotide sequence encodes a protein 525 amino acids in length,...
Published: 6/22/2010   |   Inventor(s): James Douglass, John Adelman
Keywords(s): Biological Materials, Biological Materials - DNA/RNA, Biological Materials - Receptors/Targets
Category(s): Biological Materials
A Novel Human Dopamine Receptor and its Uses (D4 subtypes - D4.2,4.4,4.7)
Technology OverviewTechnology 0250 is directed toward the isolation, characterization and pharmacological use of the human D4 dopamine receptor. The nucleotide sequence of the gene corresponding to this receptor and allelic variant thereof are provided by the invention. The invention also includes recombinant eukaryotic expression constru...
Published: 4/28/2010   |   Inventor(s): Olivier Civelli, Hubert Henri-Marie Van Tol, James Bunzow, David Grandy
Keywords(s): Biological Materials, Biological Materials - Receptors/Targets, Research Tools, Research Tools - Screening
Category(s): Research Tools
A Novel Adenosine Receptor (A3) and Uses
Technology OverviewTechnology 0223 relates to a novel mammalian adenosine receptor. The invention is directed toward the isolation, characterization and pharmacological use of the rat A3 adenosine receptor, the gene corresponding to this receptor, recombinant eudaryotic expression construct capable of expressing the rat A3 adenosine receptor ...
Published: 4/28/2010   |   Inventor(s): Olivier Civelli, Qun Zhou, Gary Stiles
Keywords(s): Biological Materials, Biological Materials - Receptors/Targets, Research Tools, Research Tools - Screening
Category(s): Research Tools
D2 Dopamine Receptor and Genes and Associated United States Patents
Technology Overview Researchers at OHSU have cloned the D2 Dopamine receptor, and have developed cell lines containing both the D2 short and long forms, which are useful in studying ligand-receptor interactions, and developing potential drug candidates for treatment of neurological diseases. Currently, the university holds numerous patents co...
Published: 4/28/2010   |   Inventor(s): Olivier Civelli, James Bunzow, David Grandy, Curtis Machida
Keywords(s): Biological Materials, Biological Materials - Receptors/Targets, Research Tools, Research Tools - Screening
Category(s): Research Tools
Yeast expressing human VDAC isoforms
Technology OverviewThe voltage dependent anion channel (VDAC) proteins are the major pathways for metabolite flux through the outer membrane. These mitochondrial membrane proteins control the flux of anions through voltage gated mechanisms. VDACs have been shown to be important in apoptotic responses and linked to certain neurodegenerative disease...
Published: 1/27/2010   |   Inventor(s): Michael Forte, Elizabeth Blachly-Dyson
Keywords(s): Biological Materials, Biological Materials - Protein/Peptides, Biological Materials - Receptors/Targets
Category(s): Biological Materials
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