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Bacterial artificial chromosome (BAC) clone containing the genome of human cytomegalovirus (HCMV) TR strain

Technology Overview The TR BAC was prepared from the TR clinical HCMV isolate. This virus is resistant to ganciclovir and cidofovir and lacks UL97 codons 591-594. The BAC clone was generated by substituting BAC DNA for the US2-US5 region of the TR genome. The TR strain infects almost any diploid endothelial or epithelial cell as well as macrophages....

Published: 9/26/2023 | Inventor(s): Jay Nelson, Michael Jarvis

Keywords(s): Biological Materials, Biological Materials - DNA/RNA, Research Tools, Research Tools - Reagents

Category(s): Biological Materials

Plasmid IE86kd able to produce the human CMV IE86 protein

Technology Overview Technology # 1266, Plasmid IE86kd has been generated which can be utilized to produce the full length human cytomegalovirus (CMV) IE86 protein. Publication Jupp R., et al., Direct interaction of the Human Cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box. J. Virology...

Published: 9/26/2023 | Inventor(s): Jay Nelson

Keywords(s): Biological Materials, Biological Materials - DNA/RNA, Research Tools, Research Tools - Reagents

Category(s): Biological Materials